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Benefits of stenting with PercuSurge GuardWire PlusTM System for myocardial salvage in acute myocardial infarction patients as observed from myocardial SPECT |
Masatsugu Nakano,1 Shohei Yamashina,2 Kenji Wagatsuma,1 and Junichi Yamazaki2 |
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Division of Interventional Cardiology, Cardiovascular Center1 and Division of Cardiovascular Center,2 Toho University Omori Hospital |
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Subjects were 56 patients with successful reperfusion from percutaneous coronary intervention performed for acute myocardial infarction, and patients were divided into the stenting with PercuSurge GuardWire PlusTM system group or PS group (17 patients) and the conventional stenting group or CS group (39 patients) for a comparative study. We calculated for total defect score (TDS) of perfusion SPECT (201Tl or 99mTc-MIBI) and 123I-BMIPP dual isotope imaging at rest. The difference between TDS of perfusion SPECT and 123I-BMIPP was classified a mismatch. Results of myocardial SPECT showed the mismatch in TDS was significantly higher in the PS group (p < 0.05). The rate of change in left ventricular end diastolic volume from the acute to chronic phase was significantly lower in the PS group (p < 0.05). Myocardial SPECT showed PS group to have better results for myocardial salvage than CS group, as well as contributing to inhibition of left ventricular remodeling. |
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Keyword: embolic protection device, no-reflow, myocardial SPECT, acute myocardial infarction |
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